Innovative mRNA vaccine against NSCLC
Designing a platform of targeted polymeric nanoparticles
for efficient personalized therapy.
Innovative mRNA vaccine against NSCLC
Designing a platform of targeted polymeric nanoparticles
for efficient personalized therapy.
About the project
We aim to design a personalized enhanced and combined nano-immunotherapeutic approach to treat lung cancer patients, based on the use of proprietary polymeric nanoparticles encapsulating nucleic acids as active principles.
These nucleic acids will:
a) act as antigens to immunize patients against tumor antigens and achieve the self-killing of tumor cells (mRNA cancer vaccination); and
b) immunomodulate the TME by silencing key immunosuppressor genes (targeted therapy).
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