Innovative mRNA vaccine against NSCLC

Designing a platform of targeted polymeric nanoparticles
for efficient personalized therapy.

Innovative mRNA vaccine against NSCLC

Designing a platform of targeted polymeric nanoparticles
for efficient personalized therapy.

About the project

We aim to design a personalized enhanced and combined nano-immunotherapeutic approach to treat lung cancer patients, based on the use of proprietary polymeric nanoparticles encapsulating nucleic acids as active principles.

These nucleic acids will:

a) act as antigens to immunize patients against tumor antigens and achieve the self-killing of tumor cells (mRNA cancer vaccination); and

b) immunomodulate the TME by silencing key immunosuppressor genes (targeted therapy).

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The project is carried out with partners from different fields, building a multidisciplinary and transversal consortium. Learn more about the members and their research profiles.

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